• Hammond, Geoffrey L.

    Titles
    Affiliate Investigator, CFRI
    Professor & Department Head, Department of Cellular and Physiological Sciences, University of British Columbia
    Tier I Canada Research Chair, Reproductive Health
    Degrees / Designations
    B.Sc., M.Sc., PhD
    Primary Area of Research
    Reproduction & Healthy Pregnancy
    Secondary Area(s) of Research
    Diabetes, Nutrition & Metabolism (Nutrition & Metabolism)
    Phone
    604-822-2498
    Fax
    Lab Phone
    Mailing Address
    Department of Cellular & Physiological Sciences
    UBC Faculty of Medicine
    2350 Health Sciences Mall, Unit 1340
    Life Sciences Centre
    Vancouver, BC V6T 1Z3
    Affiliate Websites
    Research Areas
    • Steroids in growth and development
    • Reproductive health
    • Nutrition
    Summary
    Steroid hormones control a wide range of normal biological processes but are also implicated in several disease processes including reproductive disorders, inflammation, diabetes, cardiovascular disease, and hormone-dependent cancers of male and female reproductive tissues. Synthetic steroids that act as agonists or antagonists are used widely as pharmacologic agents. The way steroids gain access to their target tissues is poorly understood. However, access is influenced primarily by two high affinity steroid-binding proteins in the blood: corticosteroid binding globulin (CBG) and sex hormone-binding globulin (SHBG). These two plasma proteins bind the glucocorticoids and sex steroids, respectively. By applying a combination of molecular biological, biochemical and physiological approaches we have gained new information about how CBG and SHBG are produced and function with respect to normal development and aging, and how they are involved in disease processes.
    Current Projects
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    Research Group Members